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Duke University provides secure, accessible AI tools for students, staff, and researchers to explore, build, and integrate AI into their work. Resources and training are available for all experience levels. Find the one that's right for you.
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Tools for Everyday Use
ChatGPT
Best for general-purpose tasks — writing, research, coding, brainstorming creative or public-facing queries.
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Microsoft CoPilot
Designed to work with Microsoft 365 and approved for use within the Duke Health community.
Duke Tools, Model Exploration, and Custom Development
DukeGPT
For Duke-specific questions and internal tools, it is best for testing and comparing AI models.
MyGPT Builder
Create custom Ai environments within a secure, sandboxed environment.
AI Gateway (API Keys)
The AI Gateway provides Duke developers and researchers access to LiteLLM API keys.
Note for the Duke Health Community: Currently, Duke Health Technology Solutions (DHTS) and Duke University Health System (DUHS) Compliance have determined that some of these tools, including ChatGPT, DukeGPT, MyGPT Builder, and AI Gateway, are not approved for use within the Duke Health environment.
Duke Health provides guidance and approved tools for the responsible use of generative AI. A current list of available tools and office hours for assistance can be found on the Duke Health Generative AI page.
For policy questions, please reach out to your departmental leadership or compliance@dm.duke.edu.
Which Tool Is Right For Me?
What are the benefits and differences between ChatGPT and DukeGPT? Here’s a quick guide: use ChatGPT for general, public tasks, and DukeGPT for anything tied to Duke or requiring extra privacy. Note neither tool is approved for sensitive data (e.g., PHI).
Here are the key benefits of each:
ChatGPT
ChatGPT is openAI’s commercial AI chatbot, available through Duke’s educational license.
Best for:
- General-purpose tasks — writing, research, coding, brainstorming creative or public-facing queries
- Academic and Research Support on the University side
Key features:
- Access to latest OpenAI models
- Built-in tools: code interpreter, image generation, file uploads
- Not linked to Duke systems
DukeGPT
This is Duke’s campus-specific AI tool, hosted and managed by Duke OIT for enhanced privacy and integration.
Best for:
- Testing and comparing different AI models
- Duke-specific questions, internal tools, sensitive tasks
Key features:
- On-prem AI models
- Data stays private within Duke’s systems
- Access to Duke-specific knowledge (e.g., directory, teaching tools)
- Multiple AI models, including open-source options
- Safe for institutional and educational use
Create a self-contained virtual resource with MyGPT Builder, running a chatbot to use for your own academic, work, or personal projects.
Available to: Students, Faculty, and Staff (university)
Pricing: Determined by needs
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Copilot is powerful, built on Large Language Models (LLMs) or advanced tools designed to predict and generate text based on your internal data (emails, reports, presentations, articles, etc.).
Available to: Students, Faculty, and Staff (university and health system)
Pricing: Free
Access: Microsoft Copilot (login with NetID)
The AI Gateway for Developers allows you to build your own AI services using LiteLLM as the AI back-end (access the proxy service offered by LiteLLM [cloud or BYOkey]).
What is the difference between each service?
| Tool | Target Audience | Use | Model Access | Cost | Security & Privacy |
|---|---|---|---|---|---|
| ChatGPT | All Duke University users | General purpose chatbot use with standard ChatGPT interface | OpenAI's ChatGPT only (GPT-5 or equivalent base model) | Pre-paid, or reduced cost | Sensitive (no PHI), (governed by institutional agreement) |
| DukeGPT | All Duke University users | Exploring AI models, learning | Curated selection of open-source and cloud models | No cost for basic use | Sensitive (no PHI), (Duke-managed, data-protected) |
| MyGPT Builder | University faculty, researchers, staff | Custom AI environments, course-/department-specific tools | Curated selection of open-source and cloud models, others by request (full admin control, dedicated instance) | Cost-recovery for some models, usage-based | Sensitive (no PHI), (Dedicated, sandboxed) |
| AI Gateway | Developers, advanced users | Building AI-powered apps and tools | Curated selection of open-source and cloud models, others by request, BYOKey for cloud (API key access, full customization) | Cost-recovery service, usage-based | Sensitive (no PHI), (Secure API, user-managed) |
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An overview of DukeGPT.
Other Duke AI Resources
- In The Loop, the Innovation Co-Lab's AI-focused blog
- Duke Science & Technology - Exploring the benefits, ethics and potential impacts of AI on our community
- Society-Centered AI Initiative - Designed to incubate research on the co-evolution of artificial intelligence and human behavior.
- Let's Not Know Together - A collection of voices of students and educators who are collectively making sense of how AI fits—if at all—in their learning journeys.
Join the Duke AI Suite User Group on Microsoft Teams for peer-to-peer support.
For additional types of support and policy information, visit AI at Duke:
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For service-specific inquiries, email aisuitesupport@duke.edu.